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KMID : 1023420160160010070
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Journal of Dental Hygiene Science
2016 Volume.16 No. 1 p.70 ~ p.76
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A Biocompatibility Evaluation of Hydroxyapaite·Titania Surface for Dental Implant
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Kang Min-Kyung
Bae Sung-Suk
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Abstract
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The objective of this study was to fabricate hydroxyapatite (HA) containing titania layer by HA blasting and anodization method to obtain advantagesof both methods and evaluated biocompatibility. To fabricate the HA containing titania layer on titanium, HA blasting treatment was performedfollowed by microarc oxidation (MAO) using the electrolyte solution of 0.04 M ?-glycerol phosphate disodium salt n-hydrate and 0.4 M calciumacetate n-hydrate on the condition of various applied voltages (100, 150, 200, 250 V) for 3 minutes. The experimental group was divided accordingto the surface treatment procedure: SM (simple machined polishing treatment), HA, MAO, HA＋MAO 100, HA＋MAO 150, HA＋MAO 200, HA＋MAO 250. The wettability of surface was observed by contact angle measurement. Biocompatibility was evaluated by cell adhesion, and celldifferentiation including alkaline phosphatase activity and calcium concentration with MC3T3-E1 cells. The porous titanium oxide containing HA wasformed at 150 and 200 V. These surfaces had a more hydrophilic characteristic. Biocompatibility was demonstrated that HA·titania compositelayer on titanium showed enhanced cell adhesion, and cell differentiation. Therefore, these results suggested that HA containing titania layer ontitanium was improved biological properties that could be applied as material for dental implant system.
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KEYWORD
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Anodization, Blasting, Dental implants, Hydroxyapatite, Titania
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